VMSpc only runs on Windows. However Macs can run Windows. There are different methods of doing this. One is by using a virtual Windows session through the Mac OS. There are a number of programs that can do this. The most popular are Parallels Desktop and VMWare Fusion. There is also an open source program called Virtual Box which is free of charge. Another method is by partitioning the hard drive and running windows directly from the Mac separate from its own OS. This only works if the Mac has an Intel processor. This is accomplished through using Boot Camp which is included in Mac OS 10.5 and later. Follow this link for more information on using Boot Camp: http://support.apple.com/kb/ht1461